A Multi-centre Trial on Targeted Microwave Ablation (TMA) for Localized Prostate Cancer Using Organ Based Tracking (OBT) Navigation
This study is to investigate the efficacy of Targeted Microwave Ablation (TMA) under MRI-Ultrasound fusion and organ-based tracking (OBT) navigation in localized prostate cancer (PCa) in a multi-centre trial.
• Men aged between 45 - 75 years
• Life expectancy \> 10 years upon recruitment
• Able to understand the trial and can provide informed and written consent, dated and signed before the enrollment and before any exam required by the trial
• Localized low or intermediate risk prostate cancer diagnosed on MRI-Ultrasound fusion targeted biopsy
• Organ-confined prostate cancer on MRI
• PSA \< 20 ng/mL
• 1-2 MRI visible lesion present and size ≤15mm, with targeted biopsy showing:
‣ ISUP grade group 2 or 3, or
⁃ ISUP grade group 1 with tumor size ≥10mm